Precision Medicine- Is There an Amazing Future?

Precision medicine is the technology in its continuously evolving state where it provides different specific targets for different individuals. Scientists and researchers have an evolving approach to the treatment and prevention of disease, taking into account their genes differences in , environment and lifestyle for each .” This approach allows clinicians and researchers to more accurately assess which treatment and prevention strategies work for which group in a particular disease and it contradicts the one-size-fits-all model in which disease treatment and prevention strategies are developed for the average person.

InoSights of precision medicine

Precision medicine (PM) is a medical model that provides the constructive interface that used in the optimization of health and with this approach it improves medical decisions, treatments, methods, or products are tailored to a subgroup of patients, rather than one – a drug – suits all models. In the proposed precision medical system, diagnostic testing is often used to select appropriate treatments based on the patient’s genetic material or other molecular or cellular analysis.

Precision Medicine
Precision Medicine

Tools used in precision medicine may include molecular diagnosis, imaging, and analysis. Although the term “precision medicine” for our readers is very new but this concept has been a part of health care for many years.

For example, a person in need of plasma donation will not receive blood from a randomly selected donor; instead, the donor’s blood type is matched with the recipient to reduce the risk of complications.  Researchers hope that this approach will expand in many areas of health and wellness in the coming years.

How is precision medicine different from the Personalised medicine?

First of all it is really clear that these two terms contains the different nature like sun or moon but we can say that they have the same fundamental base with great sounding and Explaining the difference from the general term equivalent to personal medicine, the National Research Council states:

Precision medicine refers to the tailoring of medical treatment to the individual characteristics of each patient. This does not literally mean the creation of drugs or medical devices specific to the patient, but the ability to classify them into subgroups that are different for a particular disease, the biology of those diseases, or the development in their response to a specific treatment.

Preventive or medical intervention can then focus on those who benefit, leaving costs and side effects for those who do not. Although the term ‘personalised medicine’ is also used to express this meaning, the term can sometimes be misunderstood and specific treatments can be devised for each individual.

On the other hand, the term “precision medicine” goes beyond the choice of treatments to create specific medical products for specific individuals irrespective to their genes and DNA.

What are the benefits of accurate Medicine?

Precision medicine is like the personal assistant which is used to analyse our daily routine understand better many things – including the environment, lifestyle and heredity that play a role in the patient’s health, illness or condition. This information allows them to more accurately assess which treatments are most effective and safe, or how to prevent the disease from its first onset.

There are also proposed advantages in which it will give the revolutionary change to the humans life as well as society are as follows :-

Precision for medicine

Susceptibility and Analysation

Scientists and researchers are proposed the wellness of the system through analysation of the daily routine and the nature of the genes which gives the clear cut idea its efficency of this technology.

Improve disease detection

Due to the proper analysation and records doctors can easily find out the early detection of the disease which constitutes the better diagnosis.

Early notice of disease progression

It acts like the personal bodyguard which provides the shielding surface and early detection of the disease and if we compare with present medical system we get the medicines on treatment of that disease but in this case we get the early diagnosis before disease targets successfully.

Optimise disease prevention strategies

It is used to provide the better strategies for any disease diagnosis where doctors can make the strategies and plans according to the early treatment reports.

Therefore with respect to this there are also other benefits for effectively consideration of its nature.

  1. Prescribe more effective medications

2. Avoid taking the side effects of drugs

3. Important principles in precision medicine

It requires a high level of specialized knowledge to fully understand the many scientific terms used to describe the progress and challenges of precision medicine, which is an obstacle to the providers who provide patients with the exact medicine drug, and its limitations. Although most people are aware of the concept of DNA and its basic role in many diseases but these principles provides the complete picture of how and why it can provide explanations for many of the following conditions.

Genomics

It is the important principle in the precision medicine as it provides the better analysation through the genetic material of an organism. DNA contains genes that control the function of coding regions or proteins, as well as non-coding sequences that perform regulatory functions. The study of these materials is genomics.

Genetics

A gene is a subset of a gene that gives signals to a molecule that has a specific function, such as a person’s eye color, blood type, or predisposition to certain diseases. Genes can inherit mutations as they pass through families, resulting in heredity. Variations in a person’s phenotype, or the amount of physical or behavioral traits that he or she observes, are caused by the combination of individual genes to produce those traits. Researchers are still exploring very complex relationships between genes and diseases.

Genetic sequence

Genetic sequencing, or DNA sequencing, is the process of determining the sequence of four chemical building blocks (adenine, guanine, cytosine, and thymine) of an individual organism. The sequence of these chemicals in each strand of DNA determines the type of genetic information involved in a segment of DNA.

DNA and Genomics
Gene & DNA

Researchers can identify which classes of DNA molecules contain genes and contain control information, allowing them to distinguish between certain traits and individuals that do not. The human gene contains approximately 3 billion pairs of four chemical bases of DNA, all of which provide an “instruction manual” for an organism.

Next generation sequencing

The next generation is a collection of sequencing methods that further increase the speed and range of the gene sequence. Instead of sorting an individual’s entire genetic code from start to finish, Next-Gene technology uses a piece of a person’s DNA called “reads”, and then use algorithms to compare DNA library results to fill in the blanks.

Any differences or mutations in the process will be noted. This principle provide an edge in precision medicine that allow labs to complete this process quickly, which will help meet the growing demand for their services. These methods have been developed and improved as life sciences companies rush to provide researchers and health care organizations with one of the tools needed for accurate care.

Pharmacogenetics

Pharmacogenetics is the study of how genetic differences affect the metabolic pathways of drugs or how individuals respond to specific drug drug interventions based on their specific genetic makeup. This knowledge is the basis for many specific medicine efforts, such as selecting individual drug combinations to attack a specific type of cancer. Before prescribing a drug, providers may order a genetic test to determine if the person has a genetic test that minimizes drug effect.

Pharmacogenetics (often interchangeable with pharmacogenetics) are also important for safety drug safety research and to identify potential adverse drug – drug or drug – genetic interactions.

Biogenetic code

Biogenetic codes is widely used in all types of clinical practice to indicate the occurrence of a disease, infection, poisoning, or other process in an organism. The biogenetic codes = include key signals in the blood, antibodies after infection, thyroid hormone levels or prostate specific antigen (PSA), as well as molecular signatures indicating whether the patient is likely to respond to some advanced treatment. 

The discovery of biomarkers for cancer detection and treatment and the similarity of genetic components is one of the major branches of precision medicine research. Therefore it will be widely used principle in precision medicine structures.

Future of the precision medicine

Healthcare is the most important sector where every country should spend at least the large amount of their budget but there are very less countries which do this. Therefore it is also the concept which requires the great funding but get small portion of it that creates the loophole in this technology due to its large cost nature which is the premiere impacts of it

Precision medicine is the beginning of the involvement of the health system in the development of the exact drug. The private sector is increasingly embracing such goals, which are in line with existing value-added reimbursement and population health management programs. Combining computer science and engineering achievements with laboratory work and clinical discovery, the academy is active in the precision medicine medicine ecosystem. Similarly, pharmaceutical companies are seeking to expand their port drug portfolios, investing heavily in research and collaboration with health care providers and others.

Silicon Valley giants entrepreneurs such as Bill Gates and Mark Zuckerberg also address the need for accurate medical development: Gates recently announced a $ 50 million investment in data-based Alzheimer’s research, while Zuckerberg and his wife, Dr. Priscan Chan donated 10 million to  UCSF Institute for Computational Health Sciences to explore how best to use available datasets to generate new insights.

precision medicine definition
Precision Medicine Future

Many activities revolve around collaborations and partnerships between organizations to equip their computing power and share insights into research networks. There are Some important fundings which pushes this technology into a new leg that provides the new hope for the healthcare and medical system.

Eleven biopharmaceutical companies and the National Institutes of Health are working together for a $215 million Partnership for Cancer Therapy (PACT) program as part of the Cancer Moonshot. Public-private alliances work to identify and validate biomarkers that provide immunity to a variety of cancers.

GE Healthcare and Roche Diagnostics recently announced a long-term partnership to develop the Big Data Analytics and Clinical Decision Support Platform to support accurate data research.

The Memorial Sloan Kettering Cancer Center, a Broad Institute at MIT, and Harvard, in collaboration with IBM Watson Health and Quest Diagnostics, have launched a new service that provides genetic clinical decision support. Physicians will be able to send solid diagnostic biopsies to Quest Diagnostics, which will provide data into IBM Watson Health’s Genomics Analytics tool to provide advice.

These efforts, and many in laboratories, academia and health care systems across the country, have the potential to dramatically accelerate the availability of high-target treatments for highly volatile and devastating diseases that uncover more insights into the complex differences between genetics and diseases which contains the bright future of this technology!!

FAQ On Precision Medicine

What is precision medicine used for?

Precision medicine is like the personal assistant which is used to analyse our daily routine understand better many things – including the environment, lifestyle and heredity that play a role in the patient’s health, illness or condition. This information allows them to more accurately assess which treatments are most effective and safe, or how to prevent the disease from its first onset.

What is Precision Medicine?

Precision medicine is the technology in its continuously evolving state where it provides different specific targets for different individuals. Scientists and researchers have an evolving approach to the treatment and prevention of disease, taking into account their genes differences in , environment and lifestyle for each .” This approach allows clinicians and researchers to more accurately assess which treatment and prevention strategies work for which group in a particular disease and it contradicts the one-size-fits-all model in which disease treatment and prevention strategies are developed for the average person.

What is the Future of Precision Medicine?

Precision medicine is the beginning of the involvement of the health system in the development of the exact drug. The private sector is increasingly embracing such goals, which are in line with existing value-added reimbursement and population health management programs. Combining computer science and engineering achievements with laboratory work and clinical discovery, the academy is active in the precision medicine medicine ecosystem. Similarly, pharmaceutical companies are seeking to expand their port drug portfolios, investing heavily in research and collaboration with health care providers and others.

What is Biogenetic code?

Biogenetic codes is widely used in all types of clinical practice to indicate the occurrence of a disease, infection, poisoning, or other process in an organism. The biogenetic codes = include key signals in the blood, antibodies after infection, thyroid hormone levels or prostate specific antigen (PSA), as well as molecular signatures indicating whether the patient is likely to respond to some advanced treatment. 

What is Pharmacogenetics?

Pharmacogenetics is the study of how genetic differences affect the metabolic pathways of drugs or how individuals respond to specific drug drug interventions based on their specific genetic makeup. This knowledge is the basis for many specific medicine efforts, such as selecting individual drug combinations to attack a specific type of cancer. Before prescribing a drug, providers may order a genetic test to determine if the person has a genetic test that minimizes drug effect.

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